Application

Peptide corresponding to the cell membrane-translocating sequence linked to the single-stranded DNA binding region of human p53, ′peptide 46′, corresponding to amino acids 361-382 (AAVALLPAVLLALLAP-GSRAHSSHLKSKKGQSTSRHKK). MW = 3932Da. The amount of peptide to be used must be empirically determined.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

MTS Control Peptide (25-003) can be used as a control for experiments with this peptide.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

lyophilized

Quality

A related p53 activator peptide containing the peptide 46 sequence has been used to induce apoptosis in Ew36, BL41 and SW480 cells1,2. The amount of peptide to be used must be empirically determined.

Storage and Stability

2 years at -20°C